INSERM U872 Immunologie et Cancérologie Intégratives

L'équipe

Alumni

Integrative Cancer Immunology · 15 Rue de l'Ecole de Medecine, 75006 Paris, France
Tel +33 1 4427 9101 · Fax +33 1 4427 8117 · URL http://www.ici.upmc.fr/index.shtml

PUBLICATIONS

Automated exploration of Gene Ontology term and pathway networks with ClueGO-REST.
Mlecnik B, Galon J, Bindea G.
Bioinformatics 2019 Mar 7. pii: btz163. doi: 10.1093/bioinformatics/btz163. [Epub ahead of print]
Abstract | Article

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.
Galon J, Bruni D.
Nat Rev Drug Discov. 2019 Mar;18(3):197-218. doi: 10.1038/s41573-018-0007-y. Review.
Abstract | Article

The Link between the Multiverse of Immune Microenvironments in Metastases and the Survival of Colorectal Cancer Patients.
Van den Eynde M, Mlecnik B, Bindea G, Fredriksen T, Church SE, Lafontaine L, Haicheur N, Marliot F, Angelova M, Vasaturo A, Bruni D, Jouret-Mourin A, Baldin P, Huyghe N, Haustermans K, Debucquoy A, Van Cutsem E, Gigot JF, Hubert C, Kartheuser A, Remue C, Léonard D, Valge-Archer V, Pages F, Machiels JP, Galon J.
Cancer Cell. 2018 Dec 10;34(6):1012-1026.e3. doi: 10.1016/j.ccell.2018.11.003.
Abstract | Article

Quantifying Immunoscore performance - Authors' reply.
Pages F, Mlecnik B, Galon J.
Lancet. 2018 Nov 3;392(10158):1624-1625. doi: 10.1016/S0140-6736(18)32385-7. No abstract available.
Abstract | Article

Evolution of Metastases in Space and Time under Immune Selection.
Angelova M, Mlecnik B, Vasaturo A, Bindea G, Fredriksen T, Lafontaine L, Buttard B, Morgand E, Bruni D, Jouret-Mourin A, Hubert C, Kartheuser A, Humblet Y, Ceccarelli M, Syed N, Marincola FM, Bedognetti D, Van den Eynde M, Galon J.
Cell. 2018 Oct 18;175(3):751-765.e16. doi: 10.1016/j.cell.2018.09.018. Epub 2018 Oct 11.
Abstract | Article

LBA-010Prognostic utility of immune markers and validation of Immunoscore in stage III colon carcinoma patients treated with adjuvant FOLFOX in a phase III trial (NCCTG N0147; Alliance).
Sinicrope Frank A, Shi Q, Hermitte F, Heying E, Benson Al B, Gill S, Goldberg Richard M, Kahlenberg M, Nair S, Shields A, Sargent D, Galon J, Alberts Steven R.
Ann Oncol. 2017 Jun 1;28(suppl_3). doi: 10.1093/annonc/mdx302.009. No abstract available.
Abstract | Article

Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy).
Ascierto PA, Brugarolas J, Buonaguro L, Butterfield LH, Carbone D, Daniele B, Ferris R, Fox BA, Galon J, Gridelli C, Kaufman HL, Klebanoff CA, Melero I, Nathan P, Paulos CM, Ruella M, Sullivan R, Zarour H, Puzanov I.
J Immunother Cancer. 2018 Jul 11;6(1):69. doi: 10.1186/s40425-018-0377-z. Review.
Abstract | Article

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment.
Foucher ED, Ghigo C, Chouaib S, Galon J, Iovanna J, Olive D.
Front Immunol. 2018 May 14;9:1044. doi: 10.3389/fimmu.2018.01044. eCollection 2018. Review.
Abstract | Article

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.
Pages F, Mlecnik B, Marliot F, Bindea G, Ou FS, Bifulco C, Lugli A, Zlobec I, Rau TT, Berger MD, Nagtegaal ID, Vink-Borger E, Hartmann A, Geppert C, Kolwelter J, Merkel S, Grützmann R, Van den Eynde M, Jouret-Mourin A, Kartheuser A, Leonard D, Remue C, Wang JY, Bavi P, Roehrl MHA, Ohashi PS, Nguyen LT, Han S, MacGregor HL, Hafezi-Bakhtiari S, Wouters BG, Masucci GV, Andersson EK, Zavadova E, Vocka M, Spacek J, Petruzelka L, Konopasek B, Dundr P, Skalova H, Nemejcova K, Botti G, Tatangelo F, Delrio P, Ciliberto G, Maio M, Laghi L, Grizzi F, Fredriksen T, Buttard B, Angelova M, Vasaturo A, Maby P, Church SE, Angell HK, Lafontaine L, Bruni D, El Sissy C, Haicheur N, Kirilovsky A, Berger A, Lagorce C, Meyers JP, Paustian C, Feng Z, Ballesteros-Merino C, Dijkstra J, van de Water C, van Lent-van Vliet S, Knijn N, Musina AM, Scripcariu DV, Popivanova B, Xu M, Fujita T, Hazama S, Suzuki N, Nagano H, Okuno K, Torigoe T, Sato N, Furuhata T, Takemasa I, Itoh K, Patel PS, Vora HH, Shah B, Patel JB, Rajvik KN, Pandya SJ, Shukla SN, Wang Y, Zhang G, Kawakami Y, Marincola FM, Ascierto PA, Sargent DJ, Fox BA, Galon J.
Lancet. 2018 May 26;391(10135):2128-2139. doi: 10.1016/S0140-6736(18)30789-X. Epub 2018 May 10.
Abstract | Article

Regulation of CTL Infiltration Within the Tumor Microenvironment.
Church SE, Galon J.
J Immunother Cancer. 2017;1036:33-49. doi: 10.1007/978-3-319-67577-0_3. Review.
Abstract | Article

Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.
Gnjatic S, Bronte V, Brunet LR, Butler MO, Disis ML, Galon J, Hakansson LG, Hanks BA, Karanikas V, Khleif SN, Kirkwood JM, Miller LD, Schendel DJ, Tanneau I, Wigginton JM, Butterfield LH.
Adv Exp Med Biol. 2017 May 16;5:44. doi: 10.1186/s40425-017-0243-4. eCollection 2017. Review.
Abstract | Article

Comprehensive functional analysis of large lists of genes and proteins.
Mlecnik B, Galon J, Bindea G.
J Proteomics. 2017 Mar 22. pii: S1874-3919(17)30100-8.
Abstract | Article

Focus on the Immunoscore and its potential clinical implications.
El Sissy C, Marliot F, Haicheur N, Kirilovsky A, Scripcariu D, Lagorce-Pages C, Galon J, Pages F.
Ann Pathol. 2017 Feb;37(1):29-38. doi: 10.1016/j.annpat.2016.12.010.
Abstract | Article

Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015.
Galon J, Fox BA, Bifulco CB, Masucci G, Rau T, Botti G, Marincola FM, Ciliberto G, Pages F, Ascierto PA, Capone M.
J Transl Med. 2016 Sep 20;14:273. doi: 10.1186/s12967-016-1029-z.
Abstract | Article

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.
Marigo I, Zilio S, Desantis G, Mlecnik B, Agnellini AH, Ugel S, Sasso MS, Qualls JE, Kratochvill F, Zanovello P, Molon B, Ries CH, Runza V, Hoves S, Bilocq AM, Bindea G, Mazza EM, Bicciato S, Galon J, Murray PJ, Bronte V.
Cancer Cell. 2016 Sep 12;30(3):377-90. doi: 10.1016/j.ccell.2016.08.004.
Abstract | Article

Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.
Buque A, Bloy N, Aranda F, Cremer I, Eggermont A, Fridman WH, Fucikova J, Galon J, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2016 Mar 10;5(6):e1149674. doi: 10.1080/2162402X.2016.1149674. eCollection 2016 Jun. Review.
Abstract | Article

Frameshift mutations, neoantigens and tumor-specific CD8(+) T cells in microsatellite unstable colorectal cancers.
Maby P, Galon J, Latouche JB.
Oncoimmunology. 2015 Nov 24;5(5):e1115943. doi: 10.1080/2162402X.2015.1115943. eCollection 2016.
Abstract | Article

Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule.
Kaufman HL, Butterfield LH, Coulie PG, Demaria S, Ferris RL, Galon J, Khleif SN, Mellman I, Ohashi PS, Overwijk WW, Topalian SL, Marincola FM.
J Immunother Cancer. 2016 Jun 21;4:37. doi: 10.1186/s40425-016-0142-0. eCollection 2016.
Abstract | Article

Additional Support for the Introduction of Immune Cell Quantification in Colorectal Cancer Classification.
Ferris RL, Galon J.
J Natl Cancer Inst. 2016 May 12;108(8). pii: djw033. doi: 10.1093/jnci/djw033.
Abstract | Article

Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy.
Iribarren K, Bloy N, Buque A, Cremer I, Eggermont A, Fridman WH, Fucikova J, Galon J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Sep 2;5(3):e1088631. eCollection 2016 Mar. Review.
Abstract | Article

Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients.
Kirilovsky A, Marliot F, El Sissy C, Haicheur N, Galon J, Pages F.
Int Immunol. 2016 Aug;28(8):373-82. doi: 10.1093/intimm/dxw021. Epub 2016 Apr 27. Review.
Abstract | Article

Trial Watch-Oncolytic viruses and cancer therapy.
Pol J, Buque A, Aranda F, Bloy N, Cremer I, Eggermont A, Erbs P, Fucikova J, Galon J, Limacher JM, Preville X, Sautes-Fridman C, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Dec 8;5(2):e1117740. eCollection 2016 Feb. Review.
Abstract | Article

Trial Watch-Immunostimulation with cytokines in cancer therapy.
Vacchelli E, Aranda F, Bloy N, Buque A, Cremer I, Eggermont A, Fridman WH, Fucikova J, Galon J, Spisek R, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Dec 8;5(2):e1115942. eCollection 2016 Feb. Review.
Abstract | Article

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.
Mlecnik B*, Bindea G*, Angell HK, Maby P, Angelova M, Tougeron D, Church SE, Lafontaine L, Fischer M, Fredriksen T, Sasso M, Bilocq AM, Kirilovsky A, Obenauf AC, Hamieh M, Berger A, Bruneval P, Tuech JJ, Sabourin JC, Le Pessot F, Mauillon J, Rafii A, Laurent-Puig P, Speicher MR, Trajanoski Z, Michel P, Sesboue R, Frebourg T, Pages F, Valge-Archer V, Latouche JB, Galon J.
Immunity. 2016 Mar 15;44(3):698-711. doi: 10.1016/j.immuni.2016.02.025.
Abstract | Article

Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials.
Kohrt HE, Tumeh PC, Benson D, Bhardwaj N, Brody J, Formenti S, Fox BA, Galon J, June CH, Kalos M, Kirsch I, Kleen T, Kroemer G, Lanier L, Levy R, Lyerly HK, Maecker H, Marabelle A, Melenhorst J, Miller J, Melero I, Odunsi K, Palucka K, Peoples G, Ribas A, Robins H, Robinson W, Serafini T, Sondel P, Vivier E, Weber J, Wolchok J, Zitvogel L, Disis ML, Cheever MA; Cancer Immunotherapy Trials Network (CITN).
J Immunother Cancer. 2016 Mar 15;4:15. doi: 10.1186/s40425-016-0118-0. eCollection 2016. Review.
Abstract | Article

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
Berghoff AS, Fuchs E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K, Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J, Preusser M.
Oncoimmunology. 2015 Jun 9;5(1):e1057388. eCollection 2016.
Abstract | Article

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.
Mlecnik B*, Bindea G*, Kirilovsky A*, Angell HK, Obenauf AC, Tosolini M, Church SE, Maby P, Vasaturo A, Angelova M, Fredriksen T, Mauger S, Waldner M, Berger A, Speicher MR, Pages F, Valge-Archer V, Galon J
Sci Transl Med. 24 Feb 2016, Vol. 8, Issue 327, pp. 327ra26.
Abstract | Article

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.
Ascierto PA, Atkins M, Bifulco C, Botti G, Cochran A, Davies M, Demaria S, Dummer R, Ferrone S, Formenti S, Gajewski TF, Garbe C, Khleif S, Kiessling R, Lo R, Lorigan P, Arthur GM, Masucci G, Melero I, Mihm M, Palmieri G, Parmiani G, Puzanov I, Romero P, Schilling B, Seliger B, Stroncek D, Taube J, Tomei S, Zarour HM, Testori A, Wang E, Galon J, Ciliberto G, Mozzillo N, Marincola FM, Thurin M.
J Transl Med. 2015 Nov 30;13:374. doi: 10.1186/s12967-015-0736-1
Abstract | Article

Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.
Bowtell DD, Bohm S, Ahmed AA, Aspuria PJ, Bast RC Jr, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, Edmondson R, Fotopoulou C, Gabra H, Galon J, Gourley C, Heong V, Huntsman DG, Iwanicki M, Karlan BY, Kaye A, Lengyel E, Levine DA, Lu KH, McNeish IA, Menon U, Narod SA, Nelson BH, Nephew KP, Pharoah P, Powell DJ Jr, Ramos P, Romero IL, Scott CL, Sood AK, Stronach EA, Balkwill FR.
Nat Rev Cancer. 2015 Nov;15(11):668-79. doi: 10.1038/nrc4019. Review.
Abstract | Article

Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse.
Church SE, Galon J.
Immunity. 2015 Oct 20;43(4):631-3. doi: 10.1016/j.immuni.2015.10.004.
Abstract | Article

Trial Watch: Adoptive cell transfer for oncological indications.
Aranda F, Buque A, Bloy N, Castoldi F, Eggermont A, Cremer I, Fridman WH, Fucikova J, Galon J, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 May 5;4(11):e1046673. eCollection 2015 Nov. Review.
Abstract | Article

From mice to humans: developments in cancer immunoediting.
Teng MW, Galon J, Fridman WH, Smyth MJ.
J Clin Invest. 2015 Sep 1;125(9):3338-46. doi: 10.1172/JCI80004. Epub 2015 Aug 4.
Abstract | Article

Trial watch: Naked and vectored DNA-based anticancer vaccines.
Bloy N, Buque A, Aranda F, Castoldi F, Eggermont A, Cremer I, Sautes-Fridman C, Fucikova J, Galon J, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Apr 2;4(5):e1026531. eCollection 2015 May.
Abstract | Article

Trial Watch: Peptide-based anticancer vaccines.
Pol J, Bloy N, Buque A, Eggermont A, Cremer I, Sautes-Fridman C, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Jan 9;4(4):e974411. eCollection 2015 Apr. Review.
Abstract | Article

Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy.
Pol J, Vacchelli E, Aranda F, Castoldi F, Eggermont A, Cremer I, Sautes-Fridman C, Fucikova J, Galon J, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Mar 2;4(4):e1008866. eCollection 2015 Apr. Review.
Abstract | Article

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications.
Buque A, Bloy N, Aranda F, Castoldi F, Eggermont A, Cremer I, Fridman WH, Fucikova J, Galon J, Marabelle A, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Mar 2;4(4):e1008814. eCollection 2015 Apr. Review.
Abstract | Article

Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.
Maby P, Tougeron D, Hamieh M, Mlecnik B, Kora H, Bindea G, Angell HK, Fredriksen T, Elie N, Fauquembergue E, Drouet A, Leprince J, Benichou J, Mauillon J, Le Pessot F, Sesboue R, Tuech JJ, Sabourin JC, Michel P, Frebourg T, Galon J, Latouche JB.
Cancer Res. 2015 Sep 1;75(17):3446-55. doi: 10.1158/0008-5472.CAN-14-3051. Epub 2015 Jun 9.
Abstract | Article

Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies.
Stoll G, Bindea G, Mlecnik B, Galon J, Zitvogel L, Kroemer G.
Oncotarget. 2015 May 20;6(14):11894-909.
Abstract | Article

Trial watch: Tumor-targeting monoclonal antibodies for oncological indications.
Vacchelli E, Pol J, Bloy N, Eggermont A, Cremer I, Fridman WH, Galon J, Marabelle A, Kohrt H, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2015 Feb 3;4(1):e985940. eCollection 2015 Jan. Review.
Abstract | Article

Consensus guidelines for the detection of immunogenic cell death.
Kepp O, Senovilla L, Vitale I, Vacchelli E, Adjemian S, Agostinis P, Apetoh L, Aranda F, Barnaba V, Bloy N, Bracci L, Breckpot K, Brough D, Buque A, Castro MG, Cirone M, Colombo MI, Cremer I, Demaria S, Dini L, Eliopoulos AG, Faggioni A, Formenti SC, Fucikova J, Gabriele L, Gaipl US, Galon J, Garg A, Ghiringhelli F, Giese NA, Guo ZS, Hemminki A, Herrmann M, Hodge JW, Holdenrieder S, Honeychurch J, Hu HM, Huang X, Illidge TM, Kono K, Korbelik M, Krysko DV, Loi S, Lowenstein PR, Lugli E, Ma Y, Madeo F, Manfredi AA, Martins I, Mavilio D, Menger L, Merendino N, Michaud M, Mignot G, Mossman KL, Multhoff G, Oehler R, Palombo F, Panaretakis T, Pol J, Proietti E, Ricci JE, Riganti C, Rovere-Querini P, Rubartelli A, Sistigu A, Smyth MJ, Sonnemann J, Spisek R, Stagg J, Sukkurwala AQ, Tartour E, Thorburn A, Thorne SH, Vandenabeele P, Velotti F, Workenhe ST, Yang H, Zong WX, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Dec 13;3(9):e955691. eCollection 2014 Oct. Review.
Abstract | Article

Trial Watch: Radioimmunotherapy for oncological indications.
Bloy N, Pol J, Manic G, Vitale I, Eggermont A, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Dec 13;3(9):e954929. eCollection 2014 Oct. Review.
Abstract | Article

Trial watch: Dendritic cell-based anticancer therapy.
Bloy N, Pol J, Aranda F, Eggermont A, Cremer I, Fridman WH, Fucikova J, Galon J, Tartour E, Spisek R, Dhodapkar MV, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Dec 21;3(11):e963424. eCollection 2014 Nov. Review.
Abstract | Article

Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy.
Angelova M, Charoentong P, Hackl H, Fischer ML, Snajder R, Krogsdam AM, Waldner MJ, Bindea G, Mlecnik B, Galon J, Trajanoski Z.
Genome Biol. 2015 Mar 31;16:64. doi: 10.1186/s13059-015-0620-6.
Abstract | Article

Classification of current anticancer immunotherapies.
Galluzzi L, Vacchelli E, Bravo-San Pedro JM, Buque A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, Bracci L, Caignard A, Castelli C, Cavallo F, Celis E, Cerundolo V, Clayton A, Colombo MP, Coussens L, Dhodapkar MV, Eggermont AM, Fearon DT, Fridman WH, Fucikova J, Gabrilovich DI, Galon J, Garg A, Ghiringhelli F, Giaccone G, Gilboa E, Gnjatic S, Hoos A, Hosmalin A, Jager D, Kalinski P, Karre K, Kepp O, Kiessling R, Kirkwood JM, Klein E, Knuth A, Lewis CE, Liblau R, Lotze MT, Lugli E, Mach JP, Mattei F, Mavilio D, Melero I, Melief CJ, Mittendorf EA, Moretta L, Odunsi A, Okada H, Palucka AK, Peter ME, Pienta KJ, Porgador A, Prendergast GC, Rabinovich GA, Restifo NP, Rizvi N, Sautes-Fridman C, Schreiber H, Seliger B, Shiku H, Silva-Santos B, Smyth MJ, Speiser DE, Spisek R, Srivastava PK, Talmadge JE, Tartour E, Van Der Burg SH, Van Den Eynde BJ, Vile R, Wagner H, Weber JS, Whiteside TL, Wolchok JD, Zitvogel L, Zou W, Kroemer G.
Oncotarget. 2014 Dec 30;5(24):12472-508.
Abstract | Article

Trial Watch: Oncolytic viruses for cancer therapy.
Pol J, Bloy N, Obrist F, Eggermont A, Galon J, Cremer I, Erbs P, Limacher JM, Preville X, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jun 1;3:e28694. eCollection 2014. Review.
Abstract | Article

Trial Watch: Toll-like receptor agonists in oncological indications.
Aranda F, Vacchelli E, Obrist F, Eggermont A, Galon J, Sautes-Fridman C, Cremer I, Henrik Ter Meulen J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Aug 1;3:e29179. eCollection 2014.
Abstract | Article

Trial watch: Immunostimulatory cytokines in cancer therapy.
Vacchelli E, Aranda F, Obrist F, Eggermont A, Galon J, Cremer I, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jun 3;3:e29030. eCollection 2014.
Abstract | Article

Trial Watch: Adoptive cell transfer for anticancer immunotherapy.
Aranda F, Vacchelli E, Obrist F, Eggermont A, Galon J, Herve Fridman W, Cremer I, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 May 1;3:e28344. eCollection 2014. Review.
Abstract | Article

[Immunology and personalized medicine in oncology].
Zinzindohoue F, Zeitoun G, Berger A, Todosi AM, Marliot F, Lagorce C, Galon J, Pages F.
Bull Cancer. 2014 Jun;101 Suppl 1:S12-7. doi: 10.1684/bdc.2014.1972. Review. French.
Abstract | Article

[Intratumoral immune microenvironment and survival: the immunoscore]
Galon J, Bindea G, Mlecnik B, Angell H, Lagorce C, Todosi AM, Berger A, Pages F.
Med Sci (Paris). 2014 Apr;30(4):439-44. doi: 10.1051/medsci/20143004020. Epub 2014 May 5. Review. French.
Abstract | Article

Trial Watch: DNA vaccines for cancer therapy.
Pol J, Bloy N, Obrist F, Eggermont A, Galon J, Herve Fridman W, Cremer I, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jan 1;3(1):e28185. Epub 2014 Apr 1. Review.
Abstract | Article

Trial Watch: Chemotherapy with immunogenic cell death inducers.
Vacchelli E, Aranda F, Eggermont A, Galon J, Sautes-Fridman C, Cremer I, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jan 1;3(1):e27878. Epub 2014 Mar 1. Review.
Abstract | Article

The immune landscape of human tumors: Implications for cancer immunotherapy.
Bindea G, Mlecnik B, Angell HK, Galon J.
Oncoimmunology. 2014 Jan 1;3(1):e27456. Epub 2014 Jan 3.
Abstract | Article

Trial Watch: Immunostimulatory monoclonal antibodies in cancer therapy.
Aranda F, Vacchelli E, Eggermont A, Galon J, Fridman WH, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jan 1;3(1):e27297. Epub 2014 Feb 1.
Abstract | Article

Prognostic and predictive values of the immunoscore in patients with rectal cancer.
Anitei MG, Zeitoun G, Mlecnik B, Marliot F, Haicheur N, Todosi AM, Kirilovsky A, Lagorce C, Bindea G, Ferariu D, Danciu M, Bruneval P, Scripcariu V, Chevallier JM, Zinzindohoue F, Berger A, Galon J, Pages F.
Clin Cancer Res. 2014 Apr 1;20(7):1891-9. doi: 10.1158/1078-0432.CCR-13-2830.
Abstract | Article

Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients.
Mlecnik B, Bindea G, Angell HK, Sasso MS, Obenauf AC, Fredriksen T, Lafontaine L, Bilocq AM, Kirilovsky A, Tosolini M, Waldner M, Berger A, Fridman WH, Rafii A, Valge-Archer V, Pages F, Speicher MR, Galon J
Sci Transl Med. 2014 March 19, Vol. 6, Issue 228, p. 228ra37.
Abstract | Article

Trial Watch: Tumor-targeting monoclonal antibodies in cancer therapy.
Vacchelli E, Aranda F, Eggermont A, Galon J, Sautes-Fridman C, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2014 Jan 1;3(1):e27048. Review.
Abstract | Article

Trial Watch: Peptide vaccines in cancer therapy.
Aranda F, Vacchelli E, Eggermont A, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Dec 1;2(12):e26621. Epub 2013 Nov 4. Review.
Abstract | Article

Trial Watch: Lenalidomide-based immunochemotherapy.
Semeraro M, Vacchelli E, Eggermont A, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Nov 1;2(11):e26494. Epub 2013 Oct 21. Review.
Abstract | Article

Trial Watch: Anticancer radioimmunotherapy.
Vacchelli E, Vitale I, Tartour E, Eggermont A, Sautes-Fridman C, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Sep 1;2(9):e25595. Epub 2013 Jul 3. Review.
Abstract | Article

Trial watch: Dendritic cell-based interventions for cancer therapy.
Vacchelli E, Vitale I, Eggermont A, Fridman WH, Fucikova J, Cremer I, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Oct 1;2(10):e25771. Epub 2013 Jul 29. Review.
Abstract | Article

Towards the introduction of the Immunoscore in the classification of malignant tumors.
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pages F.
J Pathol. 2013 Oct 3, 232(2):199-209. doi: 10.1002/path.4287. Review.
Abstract | Article

Trial Watch: Toll-like receptor agonists for cancer therapy.
Vacchelli E, Eggermont A, Sautes-Fridman C, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Aug 1;2(8):e25238. Epub 2013 Jun 10. Review.
Abstract | Article

Trial Watch: Immunostimulatory cytokines.
Vacchelli E, Eggermont A, Fridman WH, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Jul 1;2(7):e24850. Epub 2013 May 7. Review.
Abstract | Article

Spatio-temporal dynamics of intratumoral cells reveal the immune landscape in human cancer.
Bindea G, Mlecnik B, Tosolini M, Kirilovsky A, Waldner M, Obenauf AC, Angell H, Frederiksen T, Lafontaine L, Berger A, Bruneval P, Fridman WH, Becker C, Speicher MR, Trajanoski Z, Galon J.
Immunity. 2013 October 17; Volume 39, Issue 4, 782-795.
Abstract | Article

Trial Watch: Oncolytic viruses for cancer therapy.
Vacchelli E, Eggermont A, Sautes-Fridman C, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Jun 1;2(6):e24612. Epub 2013 Apr 16.
Abstract | Article

The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures.
Galon J, Angell HK, Bedognetti D, Marincola FM.
Immunity. 2013 Jul 25;39(1):11-26. doi: 10.1016/j.immuni.2013.07.008.
Abstract | Article

Trial Watch: Adoptive cell transfer for anticancer immunotherapy.
Vacchelli E, Eggermont A, Fridman WH, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 May 1;2(5):e24238.
Abstract | Article

Trial watch: DNA vaccines for cancer therapy.
Senovilla L, Vacchelli E, Garcia P, Eggermont A, Fridman WH, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Apr 1;2(4):e23803.
Abstract | Article

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".
Ascierto PA, Grimaldi AM, Acquavella N, Borgognoni L, Calabro L, Cascinelli N, Cesano A, Del Vecchio M, Eggermont AM, Faries M, Ferrone S, Fox BA, Gajewski TF, Galon J, Gnjatic S, Gogas H, Kashani-Sabet M, Kaufman HL, Larkin J, Lo RS, Mantovani A, Margolin K, Melief C, McArthur G, Palmieri G, Puzanov I, Ribas A, Seliger B, Sosman J, Suenaert P, Tarhini AA, Trinchieri G, Vidal-Vanaclocha F, Wang E, Ciliberto G, Mozzillo N, Marincola FM, Thurin M.
J Transl Med. 2013 Jun 3;11:137. doi: 10.1186/1479-5876-11-137.
Abstract | Article

Trial watch: Chemotherapy with immunogenic cell death inducers.
Vacchelli E, Senovilla L, Eggermont A, Fridman WH, Galon J, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Mar 1;2(3):e23510.
Abstract | Article

From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer.
Angell H, Galon J.
Curr Opin Immunol. 2013 Apr;25(2):261-7. doi: 10.1016/j.coi.2013.03.004. Epub 2013 Apr 8.
Abstract | Article

Trial watch: Monoclonal antibodies in cancer therapy.
Vacchelli E, Eggermont A, Galon J, Sautes-Fridman C, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2013 Jan 1;2(1):e22789.
Abstract | Article

The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment.
Ascierto PA, Capone M, Urba WJ, Bifulco CB, Botti G, Lugli A, Marincola FM, Ciliberto G, Galon J, Fox BA.
J Transl Med. 2013 Mar 3;11:54. doi: 10.1186/1479-5876-11-54.
Abstract | Article

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data.
Bindea G, Galon J and Mlecnik B.
Bioinformatics. 2013 Mar 1;29(5):661-3
Abstract | Article

Trial watch: Peptide vaccines in cancer therapy.
Vacchelli E, Martins I, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2012 Dec 1;1(9):1557-1576.
Abstract | Article

Trial watch: Prognostic and predictive value of the immune infiltrate in cancer.
Senovilla L, Vacchelli E, Galon J, Adjemian S, Eggermont A, Fridman WH, Sautes-Fridman C, Ma Y, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
Oncoimmunology. 2012 Nov 1;1(8):1323-1343.
Abstract | Article

Trial watch: Dendritic cell-based interventions for cancer therapy.
Galluzzi L, Senovilla L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 Oct 1;1(7):1111-1134.
Abstract | Article

Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy.
Vacchelli E, Galluzzi L, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 Sep 1;1(6):894-907.
Abstract | Article

The Immune Microenvironment of Human Tumors: General Significance and Clinical Impact.
Fridman WH, Dieu-Nosjean MC, Pages F, Cremer I, Damotte D, Sautes-Fridman C, Galon J.
Cancer Microenviron. 2013 Aug;6(2):117-22. doi: 10.1007/s12307-012-0124-9.
Abstract | Article

Cancer classification using the Immunoscore: a worldwide task force.
Galon J, Franck P, Marincola FM, Angell HK, Thurin M, Lugli A, Zlobec I, Berger A, Bifulco C, Botti G, Tatangelo F, Britten CM, Kreiter S, Chouchane L, Delrio P, Hartmann A, Asslaber M, Maio M, Masucci GV, Mihm M, Vidal-Vanaclocha F, Allison JP, Gnjatic S, Hakansson L, Huber C, Singh-Jasuja H, Ottensmeier C, Zwierzina H, Laghi L, Grizzi F, Ohashi PS, Shaw PA, Clarke BA, Wouters BG, Kawakami Y, Hazama S, Okuno K, Wang E, O'Donnell-Tormey J, Lagorce C, Pawelec G, Nishimura MI, Hawkins R, Lapointe R, Lundqvist A, Khleif SN, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Palmqvist R, Nagtegaal ID, Wang Y, D'Arrigo C, Kopetz S, Sinicrope FA, Trinchieri G, Gajewski TF, Ascierto PA, Fox BA.
J Transl Med. 2012 Oct 3;10:205. doi: 10.1186/1479-5876-10-205
Abstract | Article

Bioinformatics for cancer immunology and immunotherapy.
Charoentong P, Angelova M, Efremova M, Gallasch R, Hackl H, Galon J, Trajanoski Z.
Cancer Immunol Immunother. 2012 Nov;61(11):1885-903.
Abstract | Article

Trial Watch: Experimental Toll-like receptor agonists for cancer therapy.
Galluzzi L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 Aug 1;1(5):699-716.
Abstract | Article

Trial Watch: Immunostimulatory cytokines.
Vacchelli E, Galluzzi L, Eggermont A, Galon J, Tartour E, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 Jul 1;1(4):493-506.
Abstract | Article

Trial Watch: Adoptive cell transfer immunotherapy.
Galluzzi L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 May 1;1(3):306-315.
Abstract | Article

Trial watch: Chemotherapy with immunogenic cell death inducers.
Vacchelli E, Galluzzi L, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Kroemer G.
Oncoimmunology. 2012 Mar 1;1(2):179-188.
Abstract | Article

Trial Watch: Monoclonal antibodies in cancer therapy.
Galluzzi L, Vacchelli E, Fridman WH, Galon J, Sautes-Fridman C, Tartour E, Zucman-Rossi J, Zitvogel L, Kroemer G.
Oncoimmunology. 2012 Jan 1;1(1):28-37.
Abstract | Article

Toward integrative cancer immunotherapy: targeting the tumor microenvironment.
Emens LA, Silverstein SC, Khleif S, Marincola FM, Galon J.
J Transl Med. 2012 Apr 10;10(1):70 [Epub ahead of print]
Abstract | Article

The immune contexture in human tumours: impact on clinical outcome.
Fridman WH, Pages F, Sautes-Fridman C, Galon J.
Nat Rev Cancer. 2012 Mar 15;12(4):298-306. doi: 10.1038/nrc3245.
Abstract | Article

The Immune Score as a New Possible Approach for the Classification of Cancer.
Galon J, Pages F, Marincola FM, Thurin M, Trinchieri G, Fox BA, Gajewski TF, Ascierto PA.
J Transl Med. 2012 Jan 3;10:1.
Abstract | Article

Defining the Critical Hurdles in Cancer Immunotherapy.
Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG, Finke JH, Galon J, Gollob JA, Gouttefangeas C, Grizzi F, Guida M, Hakansson L, Hege K, Herberman RB, Hodi FS, Hoos A, Huber C, Hwu P, Imai K, Jaffee EM, Janetzki S, June CH, Kalinski P, Kaufman HL, Kawakami K, Kawakami Y, Keilholtz U, Khleif SN, Kiessling R, Kotlan B, Kroemer G, Lapointe R, Levitsky HI, Lotze MT, Maccalli C, Maio M, Marschner JP, Mastrangelo MJ, Masucci G, Melero I, Nelief C, Murphy WJ, Nelson B, Nicolini A, Nishimura MI, Odunsi K, Ohashi PS, O'Donnell-Tormey J, Old LJ, Ottensmeier C, Papamichail M, Parmiani G, Pawelec G, Proietti E, Qin S, Rees R, Ribas A, Ridolfi R, Ritter G, Rivoltini L, Romero PJ, Salem ML, Scheper RJ, Seliger B, Sharma P, Shiku H, Singh-Jasuja H, Song W, Straten PT, Tahara H, Tian Z, van Der Burg SH, von Hoegen P, Wang E, Welters MJ, Winter H, Withington T, Wolchok JD, Xiao W, Zitvogel L, Zwierzina H, Marincola FM, Gajewski TF, Wigginton JM, Disis ML.
J Transl Med. 2011 Dec 14;9(1):214. [Epub ahead of print]
Abstract | Article

Prognostic and Predictive Impact of Intra- and Peritumoral Immune Infiltrates.
Fridman WH, Galon J, Pages F, Tartour E, Sautes-Fridman C, Kroemer G.
Cancer Res. 2011 Sep 1;71(17):5601-5. Epub 2011 Aug 16. Review.
Abstract | Article

Cancer immunology-analysis of host and tumor factors for personalized medicine.
Ogino S, Galon J, Fuchs CS, Dranoff G.
Nat Rev Clin Oncol. 2011 Aug 9. doi: 10.1038/nrclinonc.2011.122. [Epub ahead of print]
Abstract | Article

The prognostic impact of anti-cancer immune response: a novel classification of cancer patients.
Bindea G, Mlecnik B, Fridman WH, Galon J.
Semin Immunopathol. 2011 Jul;33(4):335-40. Epub 2011 Apr 5.
Abstract | Article

Future Perspectives in melanoma research: Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010".
Ascierto PA, De Maio E, Bertuzzi S, Palmieri G, Halaban R, Hendrix M, Kashani-Sabet M, Ferrone S, Wang E, Cochran A, Rivoltini L, Lee PP, Fox B, Kirkwood JM, Dansky-Ullmann C, Lehmann FF, Sznol M, Schwartzentruber DJ, Maio M, Flaherty K, Galon J, Ribas A, Yang J, Stroncek DF, Mozzillo N, Marincola FM.
J Transl Med. 2011 Mar 26;9:32.
Abstract | Article

Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, Th2, Treg, Th17) in patients with colorectal cancer.
Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, Berger A, Bruneval P, Fridman W, Pages F, Galon J.
Cancer Res. 2011 Feb 15;71(4):1263-71.
Abstract | Article

hSMG-1 is a granzyme B-associated stress-responsive protein kinase.
Meslin F, Hamai A, Mlecnik B, Rosselli F, Richon C, Jalil A, Wemhoff G, Thiery J, Galon J, Chouaib S.
J Mol Med. 2011 Apr;89(4):411-21.
Abstract | Article

Tumor immunosurveillance in human cancers.
Mlecnik B, Bindea G, Pages F, Galon J.
Cancer Metastasis Rev. 2011 Mar 8. 30(1):5-12.
Abstract | Article

Histopathological-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.
Mlecnik B, Tosolini M, Kirilovsky A, Berger A, Bindea G, Meatchi T, Bruneval P, Trajanoski Z, Fridman W-H, Pages F, Galon J.
J Clin Oncol. 2011 Feb 20;29(6):610-8. Epub 2011 Jan 18.
Abstract | Article

Immunosurveillance in human non-viral cancers.
Fridman WH, Mlecnik B, Bindea G, Pages F, Galon J
Current Opinion In Immunology 2011 Apr;23(2):272-8.
Abstract | Article

Information technology solutions for integration of biomolecular and clinical data in the identification of new cancer biomarkers and targets for therapy.
Hackl H, Stocker G, Charoentong P, Mlecnik B, Bindea G, Galon J, Trajanoski Z.
Pharmacol Ther 2010 Dec 128(3):488-98. Epub 2010 Sep 9.
Abstract | Article

Memory T-cell responses and survival in human cancer: remember to stay alive.
Camus M, Galon J.
Adv Exp Med Biol. 2010;684:166-77.
Abstract | Article

Immune Infiltration in Human Cancer: Prognostic Significance and Disease Control
Fridman WH, Galon J, Dieu-Nosjean MC, Cremer I, Fisson S, Damotte D, Pages F, Tartour E, Sautes-Fridman C
Curr Top Microbiol Immunol 2011;344:1-24.
Abstract | Article

Natural immunity to cancer in humans
Bindea G, Mlecnik B, Fridman WH, Pages F, Galon J
Current Opinion In Immunology 2010 Apr;22(2):215-22
Abstract | Article

Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction
Mlecnik B, Sanchez-Cabo F, Charoentong P, Bindea G, Pages F, Berger A, Galon J, Trajanoski Z
BMC Genomics 2010;11 Suppl 1:S7.
Abstract | Article

Biomolecular network reconstruction identifies T cell homing factors associated with survival in colorectal cancer
Mlecnik B, Tosolini M, Charoentong P, Kirilovsky A, Bindea G, Berger A, Camus M, Gillard M, Bruneval P, Fridman WH, Pages F, Trajanoski Z, Galon J
Gastroenterology 2010 Apr;138(4):1429-40. Epub 2009 Nov 10.
Abstract | Article

iLAP: a workflow-driven software for experimental protocol development, data acquisition and analysis
Stocker G, Fischer M, Rieder D, Bindea G, Kainz S, Oberstolz M, McNally JG, Trajanoski Z
BMC Bioinformatics 2009. 10(1):390
Abstract | Article

Immune infiltration in human tumors: a prognostic factor that should not be ignored
Pages F, Galon J, Dieu-Nosjean M-C, Tartour E, Sautes-Fridman C, Fridman W-H
Oncogene 2010. 29: 1093-1102
Abstract | Article

The in situ cytotoxic and memory T cells predict outcome in early-stage colorectal cancer patients
Pages F, Kirilovsky A, Mlecnik B, Tosolini M, Bindea G, Lagorce C, Wind P, Marliot F, Bruneval P, Zatloukal K, Trajanoski Z, Berger A, Fridman W-H, Galon J
J Clin Oncol 2009 Dec 10;27(35):5944-51. Epub 2009 Oct 26.
Abstract | Article

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Bindea G*, Mlecnik B*, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman W-H, Pages F, Trajanoski Z, Galon J
Bioinformatics 2009. 25(8):1091-1093
Abstract | Article

Coordination of intratumoral immune reaction and human colorectal cancer recurrence
Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman W-H, Galon J
Cancer Res 2009. 69(6):2685-93
Abstract | Article

The adaptive immunologic microenvironment in colorectal cancer: a novel perspective
Galon J, Fridman WH, Pages F
Cancer Res 2007. 67:1883-6
Abstract | Article

A new platform linking chromosomal and sequence information
Kowalska A, Bozsaky E, Ramsauer T, Rieder D, Bindea G, Lorch T, Trajanoski Z, Ambros PF
Chromosome Res 2007. 15:327-340
Abstract | Article

LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells
Tschernatsch MMO, Mlecnik B, Trajanoski Z, Zechner R, Zimmermann R
Atherosclerosis 2006 Dec;189(2):310-7. Epub 2006 Feb 21.
Abstract | Article

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce C, Tosolini M, Camus M, Berger A, Wind P, Zinzindohoue F, Bruneval P, Cugnenc P-H, Trajanoski Z, Fridman W-H, Pages F
Science 2006.313:1960-4
Abstract | Article

Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure
Abouzahr S, Bismuth G, Gaudin C, Caroll O, Van Endert P, Jalil A, Dausset J, Vergnon I, Richon C, Kauffmann A, Galon J, Raposo G, Mami-Chouaib F, Chouaib S
Proc Natl Acad Sci U S A 2006.103:1428-33
Abstract | Article

PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways
Mlecnik B, Scheideler M, Hackl H, Hartler J, Sanchez-Cabo F , Trajanoski Z
Nucleic Acids Res 2005. 33: W633-W637
Abstract | Article

Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells
Pages F, Galon J, Karaschuk G, Dudziak D, Camus M, Lazar V, Camilleri-Broet S, Lagorce-Pages C, Lebel-Binay S, Laux G, Fridman WH, Henglein B
Blood 2005.105:1632-9
Abstract | Article

Effector memory T cells, early metastasis, and survival in colorectal cancer
Pages F, Berger A, Camus M, Sanchez-Cabo F, Costes A, Molidor R, Mlecnik B, Kirilovsky A, Nilsson M, Damotte D, Meatchi T, Bruneval P, Cugnenenc PH, Trajanoski Z, Fridman WH, Galon J
N Engl J Med 2005.353:2654-66
Abstract | Article

GOLD.db: Genomics of lipid-asociated disorders database
Hackl H, Maurer M, Mlecnik B, Hartler J, Stocker G, Miranda-Saavedra D, Trajanoski Z
BMC Genomics 2004.5:93
Abstract | Article

Client-Server Environment for High-Performance Gene Expression Data Analysis
Sturn A, Mlecnik B, Pieler R, Rainer J, Truskaller T, Trajanoski Z
Bioinformatics 2003. 19:772-773
Abstract | Article

IL-18 is produced by prostate cancer cells and secreted in response to interferons
S Lebel-Binay, N Thiounn, G De Pinieux, A Vieillefond, B Debre, JY Bonnefoy, WH Fridman, F Pages
Int J Cancer 2003.106:827-35
Abstract | Article

Adoptive immunotherapy for superficial bladder cancer with autologous macrophage activated killer cells
N Thiounn, F Pages, A Mejean, JL Descotes, WH Fridman, JL Romet-Lemonne
J Urol 2002.168:2373-6
Abstract | Article

Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity
P Tang, TP Cheng, D Agnello, CY Wu, BD Hissong, WT Watford, HJ Ahn, J Galon, J Moss, M Vaughan, JJ O'Shea, M Gadina
Proc Natl Acad Sci U S A 2002.99:2625-9
Abstract | Article

Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer
F Pages, S Lebel-Binay, A Vieillefond, L Deneux, M Cambillau, O Soubrane, B Debre, D Tardy, JL Lemonne, JP Abastado, WH Fridman, N Thiounn
Clin Exp Immunol 2002.127:303-9
Abstract | Article

Glucocorticoid-inducible genes that regulate T-cell function
PR Mittelstadt, J Galon, D Franchimont, JJ O'Shea, JD Ashwell
Ernst Schering Res Found Workshop 2002.:319-39
Abstract non disponible | Article

Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
J Galon, D Franchimont, N Hiroi, G Frey, A Boettner, M Ehrhart-Bornstein, JJ O'Shea, GP Chrousos, SR Bornstein
Faseb J 2002.16:61-71
Abstract | Article

Glucocorticoids and inflammation revisited: the state of the art. NIH clinical staff conference
D Franchimont, T Kino, J Galon, GU Meduri, G Chrousos
Neuroimmunomodulation 2002.10:247-60
Abstract | Article

Positive effects of glucocorticoids on T cell function by up-regulation of IL-7 receptor alpha
D Franchimont, J Galon, MS Vacchio, S Fan, R Visconti, DM Frucht, V Geenen, GP Chrousos, JD Ashwell, JJ O'Shea
J Immunol 2002.168:2212-8
Abstract | Article

Modulation of tumor growth by inhibitory Fc(gamma) receptor expressed by human melanoma cells
L Cassard, JF Cohen-Solal, A Galinha, X Sastre-Garau, C Mathiot, J Galon, T Dorval, A Bernheim, WH Fridman, C Sautes-Fridman
J Clin Invest 2002.110:1549-57
Abstract | Article

[Clinical relevance of interleukin-18 production in the intestinal mucosa]
F Zinzindohoue, F Pages, A Berger, C Danel, V Lazar, N Thiounn, WH Fridman, PH Cugnenc
Gastroenterol Clin Biol 2001.25:761-9
Abstract non disponible | Article

Analysis of interleukin-18, interleukin-1 converting enzyme (ICE) and interleukin-18-related cytokines in Crohn's disease lesions
F Pages, V Lazar, A Berger, C Danel, S Lebel-Binay, F Zinzindohoue, P Desreumaux, C Cellier, N Thiounn, D Bellet, PH Cugnenc, WH Fridman
Eur Cytokine Netw 2001.12:97-104
Abstract | Article

Differential gene expression profile of glucocorticoids, testosterone, and dehydroepiandrosterone in human cells
M Maurer, Z Trajanoski, G Frey, N Hiroi, J Galon, HS Willenberg, PW Gold, GP Chrousos, WA Scherbaum, SR Bornstein
Horm Metab Res 2001.33:691-5
Abstract | Article

Soluble CD16 inhibits CR3 (CD11b/CD18)-mediated infection of monocytes/macrophages by opsonized primary R5 HIV-1
H Bouhlal, J Galon, MD Kazatchkine, WH Fridman, C Sautes-Fridman, N Haeffner Cavaillon
J Immunol 2001.166:3377-83
Abstract | Article

The tumor-necrosis-factor receptor-associated periodic syndrome: new mutations in TNFRSF1A, ancestral origins, genotype-phenotype studies, and evidence for further genetic heterogeneity of periodic fevers
I Aksentijevich, J Galon, M Soares, E Mansfield, K Hull, HH Oh, R Goldbach-Mansky, J Dean, B Athreya, AJ Reginato, M Henrickson, B Pons-Estel, JJ O'Shea, DL Kastner
Am J Hum Genet 2001.69:301-14
Abstract | Article

Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation
YJ Zhou, KS Magnuson, TP Cheng, M Gadina, DM Frucht, J Galon, F Candotti, RL Geahlen, PS Changelian, JJ O'Shea
Mol Cell Biol 2000.20:4371-80
Abstract | Article

Proinflammatory and antitumor properties of interleukin-18 in the gastrointestinal tract
F Pages, A Berger, S Lebel-Binay, F Zinzindohoue, C Danel, B Piqueras, O Carriere, N Thiounn, PH Cugnenc, WH Fridman
Immunol Lett 2000.75:9-14
Abstract | Article

Interleukin-18: biological properties and clinical implications
S Lebel-Binay, A Berger, F Zinzindohoue, P Cugnenc, N Thiounn, WH Fridman, F Pages
Eur Cytokine Netw 2000.11:15-26
Abstract | Article

TNFRSF1A mutations and autoinflammatory syndromes
J Galon, I Aksentijevich, MF McDermott, JJ O'Shea, DL Kastner
Curr Opin Immunol 2000.12:479-86
Abstract | Article

Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation
DM Frucht, M Aringer, J Galon, C Danning, M Brown, S Fan, M Centola, CY Wu, N Yamada, H El Gabalawy, JJ O'Shea
J Immunol 2000.164:4659-64
Abstract | Article

Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes
D Franchimont, J Galon, M Gadina, R Visconti, Y Zhou, M Aringer, DM Frucht, GP Chrousos, JJ O'Shea
J Immunol 2000.164:1768-74
Abstract | Article

Adrenal cortical activation in murine colitis
D Franchimont, G Bouma, J Galon, GW Wolkersdorfer, A Haidan, GP Chrousos, SR Bornstein
Gastroenterology 2000.119:1560-8
Abstract | Article

The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators
M Centola, G Wood, DM Frucht, J Galon, M Aringer, C Farrell, DW Kingma, ME Horwitz, E Mansfield, SM Holland, JJ O'Shea, HF Rosenberg, HL Malech, DL Kastner
Blood 2000.95:3223-31
Abstract | Article

Do glucocorticoids participate in thymocyte development?
JD Ashwell, MS Vacchio, J Galon
Immunol Today 2000.21:644-6
Abstract non disponible | Article

TGF-beta does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs
C Sudarshan, J Galon, Y Zhou, JJ O'Shea
J Immunol 1999.162:2974-81
Abstract | Article

Control of tumor development by intratumoral cytokines
F Pages, V Vives, C Sautes-Fridman, F Fossiez, A Berger, PH Cugnenc, E Tartour, WH Fridman
Immunol Lett 1999.68:135-9
Abstract | Article

Modulation of interleukin-18 expression in human colon carcinoma: consequences for tumor immune surveillance
F Pages, A Berger, B Henglein, B Piqueras, C Danel, F Zinzindohoue, N Thiounn, PH Cugnenc, WH Fridman
Int J Cancer 1999.84:326-30
Abstract | Article

Regulation of production of soluble Fc gamma receptors type III in normal and pathological conditions
I Moldovan, J Galon, I Maridonneau-Parini, S Roman Roman, C Mathiot, WH Fridman, C Sautes-Fridman
Immunol Lett 1999.68:125-34
Abstract | Article

Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
MF McDermott,I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, M Centola, E Mansfield, M Gadina, L Karenko, T Pettersson, J McCarthy, DM Frucht, M Aringer, Y Torosyan, AM Teppo, M Wilson, HM Karaarslan
Cell 1999.97:133-44
Abstract | Article

Soluble CD16 in plasma cell dyscrasias
C Mathiot, J Galon, E Tartour, JL Teillaud, T Facon, R Bataille, WH Fridman, C Sautes
Leuk Lymphoma 1999.32:467-74
Abstract | Article

Presentation of antigen in immune complexes is boosted by soluble bacterial immunoglobulin binding proteins
M Leonetti, J Galon, R Thai, C Sautes-Fridman, G Moine, A Menez
J Exp Med 1999.189:1217-28
Abstract | Article

IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells
J Galon, C Sudarshan, S Ito, D Finbloom, JJ O'Shea
J Immunol 1999.162:7256-62
Abstract | Article