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Integrative Cancer Immunology · 15 Rue de l'Ecole de Medecine, 75006 Paris, France Tel +33 1 4427 9101 · Fax +33 1 4051 0420 · URL http://www.ici.upmc.fr/index.shtml |
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| PUBLICATIONS |
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Natural immunity to cancer in humans Bindea G, Mlecnik B, Fridman WH, Pages F, Galon J Current Opinion In Immunology 2010 Mar 4. [Epub ahead of print] Abstract | Article Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction Mlecnik B, Sanchez-Cabo F, Charoentong P, Bindea G, Pages F, Berger A, Galon J, Trajanoski Z BMC Genomics 2010;11 Suppl 1:S7. Abstract | Article Biomolecular network reconstruction identifies T cell homing factors associated with survival in colorectal cancer Mlecnik B, Tosolini M, Charoentong P, Kirilovsky A, Bindea G, Berger A, Camus M, Gillard M, Bruneval P, Fridman WH, Pages F, Trajanoski Z, Galon J Gastroenterology 2009 Nov 9 (Epub ahead of print) Abstract | Article iLAP: a workflow-driven software for experimental protocol development, data acquisition and analysis Stocker G, Fischer M, Rieder D, Bindea G, Kainz S, Oberstolz M, McNally JG, Trajanoski Z BMC Bioinformatics 2009. 10(1):390 Abstract | Article Immune infiltration in human tumors: a prognostic factor that should not be ignored Pages F, Galon J, Dieu-Nosjean M-C, Tartour E, Sautes-Fridman C, Fridman W-H Oncogene 2010. 29: 1093-1102 Abstract | Article The in situ cytotoxic and memory T cells predict outcome in early-stage colorectal cancer patients Pages F, Kirilovsky A, Mlecnik B, Tosolini M, Bindea G, Lagorce C, Wind P, Marliot F, Bruneval P, Zatloukal K, Trajanoski Z, Berger A, Fridman W-H, Galon J J Clin Oncol 2009 Oct 26 Abstract | Article ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks Bindea G*, Mlecnik B*, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman W-H, Pages F, Trajanoski Z, Galon J Bioinformatics 2009. 25(8):1091-1093 Abstract | Article Coordination of intratumoral immune reaction and human colorectal cancer recurrence Camus M, Tosolini M, Mlecnik B, Pagès F, Kirilovsky A, Berger A, Costes A, Bindea G, Charoentong P, Bruneval P, Trajanoski Z, Fridman W-H, Galon J Cancer Res 2009. 69(6):2685-93 Abstract | Article The adaptive immunologic microenvironment in colorectal cancer: a novel perspective Galon J, Fridman WH, Pages F Cancer Res 2007. 67:1883-6 Abstract | Article A new platform linking chromosomal and sequence information Kowalska A, Bozsaky E, Ramsauer T, Rieder D, Bindea G, Lorch T, Trajanoski Z, Ambros PF Chromosome Res 2007. 15:327-340 Abstract | Article LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells Tschernatsch MMO, Mlecnik B, Trajanoski Z, Zechner R, Zimmermann R Atherosclerosis 2006 Abstract | Article Type, density, and location of immune cells within human colorectal tumors predict clinical outcome Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce C, Tosolini M, Camus M, Berger A, Wind P, Zinzindohoué F, Bruneval P, Cugnenc P-H, Trajanoski Z, Fridman W-H, Pagès F Science 2006.313:1960-4 Abstract | Article Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure Abouzahr S, Bismuth G, Gaudin C, Caroll O, Van Endert P, Jalil A, Dausset J, Vergnon I, Richon C, Kauffmann A, Galon J, Raposo G, Mami-Chouaib F, Chouaib S Proc Natl Acad Sci U S A 2006.103:1428-33 Abstract | Article PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways Mlecnik B, Scheideler M, Hackl H, Hartler J, Sanchez-Cabo F , Trajanoski Z Nucleic Acids Res 2005. 33: W633-W637 Abstract | Article Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells Pages F, Galon J, Karaschuk G, Dudziak D, Camus M, Lazar V, Camilleri-Broet S, Lagorce-Pages C, Lebel-Binay S, Laux G, Fridman WH, Henglein B Blood 2005.105:1632-9 Abstract | Article Effector memory T cells, early metastasis, and survival in colorectal cancer Pages F, Berger A, Camus M, Sanchez-Cabo F, Costes A, Molidor R, Mlecnik B, Kirilovsky A, Nilsson M, Damotte D, Meatchi T, Bruneval P, Cugnenenc PH, Trajanoski Z, Fridman WH, Galon J N Engl J Med 2005.353:2654-66 Abstract | Article GOLD.db: Genomics of lipid-asociated disorders database Hackl H, Maurer M, Mlecnik B, Hartler J, Stocker G, Miranda-Saavedra D, Trajanoski Z BMC Genomics 2004.5:93 Abstract | Article Client-Server Environment for High-Performance Gene Expression Data Analysis Sturn A, Mlecnik B, Pieler R, Rainer J, Truskaller T, Trajanoski Z Bioinformatics 2003. 19:772-773 Abstract | Article IL-18 is produced by prostate cancer cells and secreted in response to interferons S Lebel-Binay, N Thiounn, G De Pinieux, A Vieillefond, B Debre, JY Bonnefoy, WH Fridman, F Pages Int J Cancer 2003.106:827-35 Abstract | Article Adoptive immunotherapy for superficial bladder cancer with autologous macrophage activated killer cells N Thiounn, F Pages, A Mejean, JL Descotes, WH Fridman, JL Romet-Lemonne J Urol 2002.168:2373-6 Abstract | Article Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity P Tang, TP Cheng, D Agnello, CY Wu, BD Hissong, WT Watford, HJ Ahn, J Galon, J Moss, M Vaughan, JJ O'Shea, M Gadina Proc Natl Acad Sci U S A 2002.99:2625-9 Abstract | Article Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer F Pages, S Lebel-Binay, A Vieillefond, L Deneux, M Cambillau, O Soubrane, B Debre, D Tardy, JL Lemonne, JP Abastado, WH Fridman, N Thiounn Clin Exp Immunol 2002.127:303-9 Abstract | Article Glucocorticoid-inducible genes that regulate T-cell function PR Mittelstadt, J Galon, D Franchimont, JJ O'Shea, JD Ashwell Ernst Schering Res Found Workshop 2002.:319-39 Abstract non disponible | Article Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells J Galon, D Franchimont, N Hiroi, G Frey, A Boettner, M Ehrhart-Bornstein, JJ O'Shea, GP Chrousos, SR Bornstein Faseb J 2002.16:61-71 Abstract | Article Glucocorticoids and inflammation revisited: the state of the art. NIH clinical staff conference D Franchimont, T Kino, J Galon, GU Meduri, G Chrousos Neuroimmunomodulation 2002.10:247-60 Abstract | Article Positive effects of glucocorticoids on T cell function by up-regulation of IL-7 receptor alpha D Franchimont, J Galon, MS Vacchio, S Fan, R Visconti, DM Frucht, V Geenen, GP Chrousos, JD Ashwell, JJ O'Shea J Immunol 2002.168:2212-8 Abstract | Article Modulation of tumor growth by inhibitory Fc(gamma) receptor expressed by human melanoma cells L Cassard, JF Cohen-Solal, A Galinha, X Sastre-Garau, C Mathiot, J Galon, T Dorval, A Bernheim, WH Fridman, C Sautes-Fridman J Clin Invest 2002.110:1549-57 Abstract | Article [Clinical relevance of interleukin-18 production in the intestinal mucosa] F Zinzindohoue, F Pages, A Berger, C Danel, V Lazar, N Thiounn, WH Fridman, PH Cugnenc Gastroenterol Clin Biol 2001.25:761-9 Abstract non disponible | Article Analysis of interleukin-18, interleukin-1 converting enzyme (ICE) and interleukin-18-related cytokines in Crohn's disease lesions F Pages, V Lazar, A Berger, C Danel, S Lebel-Binay, F Zinzindohoue, P Desreumaux, C Cellier, N Thiounn, D Bellet, PH Cugnenc, WH Fridman Eur Cytokine Netw 2001.12:97-104 Abstract | Article Differential gene expression profile of glucocorticoids, testosterone, and dehydroepiandrosterone in human cells M Maurer, Z Trajanoski, G Frey, N Hiroi, J Galon, HS Willenberg, PW Gold, GP Chrousos, WA Scherbaum, SR Bornstein Horm Metab Res 2001.33:691-5 Abstract | Article Soluble CD16 inhibits CR3 (CD11b/CD18)-mediated infection of monocytes/macrophages by opsonized primary R5 HIV-1 H Bouhlal, J Galon, MD Kazatchkine, WH Fridman, C Sautes-Fridman, N Haeffner Cavaillon J Immunol 2001.166:3377-83 Abstract | Article The tumor-necrosis-factor receptor-associated periodic syndrome: new mutations in TNFRSF1A, ancestral origins, genotype-phenotype studies, and evidence for further genetic heterogeneity of periodic fevers I Aksentijevich, J Galon, M Soares, E Mansfield, K Hull, HH Oh, R Goldbach-Mansky, J Dean, B Athreya, AJ Reginato, M Henrickson, B Pons-Estel, JJ O'Shea, DL Kastner Am J Hum Genet 2001.69:301-14 Abstract | Article Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation YJ Zhou, KS Magnuson, TP Cheng, M Gadina, DM Frucht, J Galon, F Candotti, RL Geahlen, PS Changelian, JJ O'Shea Mol Cell Biol 2000.20:4371-80 Abstract | Article Proinflammatory and antitumor properties of interleukin-18 in the gastrointestinal tract F Pages, A Berger, S Lebel-Binay, F Zinzindohoue, C Danel, B Piqueras, O Carriere, N Thiounn, PH Cugnenc, WH Fridman Immunol Lett 2000.75:9-14 Abstract | Article Interleukin-18: biological properties and clinical implications S Lebel-Binay, A Berger, F Zinzindohoue, P Cugnenc, N Thiounn, WH Fridman, F Pages Eur Cytokine Netw 2000.11:15-26 Abstract | Article TNFRSF1A mutations and autoinflammatory syndromes J Galon, I Aksentijevich, MF McDermott, JJ O'Shea, DL Kastner Curr Opin Immunol 2000.12:479-86 Abstract | Article Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation DM Frucht, M Aringer, J Galon, C Danning, M Brown, S Fan, M Centola, CY Wu, N Yamada, H El Gabalawy, JJ O'Shea J Immunol 2000.164:4659-64 Abstract | Article Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes D Franchimont, J Galon, M Gadina, R Visconti, Y Zhou, M Aringer, DM Frucht, GP Chrousos, JJ O'Shea J Immunol 2000.164:1768-74 Abstract | Article Adrenal cortical activation in murine colitis D Franchimont, G Bouma, J Galon, GW Wolkersdorfer, A Haidan, GP Chrousos, SR Bornstein Gastroenterology 2000.119:1560-8 Abstract | Article The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators M Centola, G Wood, DM Frucht, J Galon, M Aringer, C Farrell, DW Kingma, ME Horwitz, E Mansfield, SM Holland, JJ O'Shea, HF Rosenberg, HL Malech, DL Kastner Blood 2000.95:3223-31 Abstract | Article Do glucocorticoids participate in thymocyte development? JD Ashwell, MS Vacchio, J Galon Immunol Today 2000.21:644-6 Abstract non disponible | Article TGF-beta does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs C Sudarshan, J Galon, Y Zhou, JJ O'Shea J Immunol 1999.162:2974-81 Abstract | Article Control of tumor development by intratumoral cytokines F Pages, V Vives, C Sautes-Fridman, F Fossiez, A Berger, PH Cugnenc, E Tartour, WH Fridman Immunol Lett 1999.68:135-9 Abstract | Article Modulation of interleukin-18 expression in human colon carcinoma: consequences for tumor immune surveillance F Pages, A Berger, B Henglein, B Piqueras, C Danel, F Zinzindohoue, N Thiounn, PH Cugnenc, WH Fridman Int J Cancer 1999.84:326-30 Abstract | Article Regulation of production of soluble Fc gamma receptors type III in normal and pathological conditions I Moldovan, J Galon, I Maridonneau-Parini, S Roman Roman, C Mathiot, WH Fridman, C Sautes-Fridman Immunol Lett 1999.68:125-34 Abstract | Article Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes MF McDermott,I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, M Centola, E Mansfield, M Gadina, L Karenko, T Pettersson, J McCarthy, DM Frucht, M Aringer, Y Torosyan, AM Teppo, M Wilson, HM Karaarslan Cell 1999.97:133-44 Abstract | Article Soluble CD16 in plasma cell dyscrasias C Mathiot, J Galon, E Tartour, JL Teillaud, T Facon, R Bataille, WH Fridman, C Sautes Leuk Lymphoma 1999.32:467-74 Abstract | Article Presentation of antigen in immune complexes is boosted by soluble bacterial immunoglobulin binding proteins M Leonetti, J Galon, R Thai, C Sautes-Fridman, G Moine, A Menez J Exp Med 1999.189:1217-28 Abstract | Article IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells J Galon, C Sudarshan, S Ito, D Finbloom, JJ O'Shea J Immunol 1999.162:7256-62 Abstract | Article |